Erythema multiforme
☆ Liphethong tsa 2022 Stiftung Warentest tse tsoang Jeremane, khotsofalo ea bareki ka ModelDerm e ne e le tlase hanyane ho feta lipuisano tse lefelloang tsa telemedicine.
Erythema multiforme minor ― Hlokomela hore litsi tsa diso li ka 'na tsa lla.
Urticaria e kanna ea nkuoa e le tlhahlobo e fapaneng.
References
Erythema multiforme (EM) ke boemo boo ho bona matheba a ikhethileng a kang sepheo a hlahang letlalong le lera la mucous ka lebaka la karabelo ea 'mele ea ho itšireletsa mafung. Le hoja hangata e bakoa ke tšoaetso ea kokoana-hloko, haholo-holo herpes simplex virus (HSV) , kapa meriana e itseng, sesosa se ntse se sa tsejoe maemong a mangata. Ho phekola EM ho shebane le ho fokotsa matšoao ho sebelisa litlolo tse nang le li-steroid kapa li-antihistamine. Ho laola EM e iphetang hangata ho sebetsa haholo ha ho etselitsoe mokuli e mong le e mong. Mekhoa ea pele e kenyelletsa phekolo ea molomo le ea lihlooho. Tsena li kenyelletsa li-corticosteroids le li-antiviral. Litlhare tsa lihlooho li na le litlolo tse matla tsa steroid le litharollo bakeng sa lera la mucous le amehileng. Bakeng sa bakuli ba sa arabeleng ho li-antiviral, khetho ea bobeli e kenyelletsa meriana e thibelang 'mele oa ho itšireletsa mafung, lithibela-mafu, meriana ea anthelmintic le e thibelang malaria.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Maemong a mangata, erythema multiforme e bonolo e itsamaela ka boyona nakong ea libeke tse 2 ho isa ho tse 4. Lefu la Stevens-Johnson, boemo bo matla bo amang lera la mucous, le ka nka libeke tse 6. Li-steroid ha li khothalletsoe maemong a bobebe. Hore na li-steroid li lokela ho sebelisoa bakeng sa erythema multiforme e matla ha ho tsejoe hantle kaha ha ho liphuputso tse hlakileng tse tsoang liphuputsong tse sa lebelloang tse bontšang hore na ke bana bafe ba ka ruang molemo kalafong ena.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Re fana ka nyeoe ea erythema multiforme (EM) ea molomo e bakoang ke TMP/SMX , e bontšang liso tsa molomo le molomo ntle le letlalo. Sena se totobatsa tlhoko ea ho e khetholla ho mafu a mang a liso tsa ka molomong. Mokuli o ile a fumana phekolo ea matšoao le matlapa a prednisolone, a lebisang ntlafatsong ka mor'a ho emisa phekolo ea TMP / SMX.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme ke karabelo e amang letlalo le ka linako tse ling mucosa, e hlahisoang ke sesole sa 'mele. Ka tloaelo, e bonahala e le maqeba a kang a sepheo, a ka 'nang a bonahala a le mong, a ipheta, kapa a phehella. Hangata maqeba ana a ama lipheletsong, haholo-holo bokantle ba tsona. Lisosa tse ka sehloohong li kenyelletsa tšoaetso e kang herpes simplex kokoana-hloko le Mycoplasma pneumoniae, hammoho le meriana e itseng, liente le mafu a autoimmune. Ho khetholla erythema multiforme ho tloha ho urticaria ho itšetlehile ka nako ea liso; erythema multiforme maqeba a lula a tsitsitse bonyane matsatsi a supileng, athe maqeba a urticaria hangata a nyamela ka mor'a letsatsi. Leha e ts'oana, ho bohlokoa ho khetholla erythema multiforme ho tsoa ho lefu le matla la Stevens-Johnson, leo hangata le hlahisang makhopho a erythematous kapa purpuric a nang le machache. Ho laola erythema multiforme ho kenyelletsa ho imoloha ha matšoao ka li-topical steroids kapa li-antihistamine le ho rarolla sesosa. Bakeng sa linyeoe tse pheta-phetoang tse amanang le kokoana-hloko ea herpes simplex, phekolo ea prophylactic ea antiviral e khothalletsoa. Ho ameha ho hoholo ha mucosal ho ka hloka hore motho a kene sepetlele bakeng sa maro a kenang methapong le ho nkeloa sebaka ke electrolyte.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Boemo bo fapana ho tloha ho lekhopho le bonolo, le ikemetseng ho ea ho mofuta o matla, o behang bophelo kotsing o tsejoang e le erythema multiforme e kholo e amang lera la mucous. Ho hlaseloa ha lera la mucous kapa boteng ba li-bulla ke matšoao a bohlokoa a ho tiea.
- Erythema multiforme minor: liphofu tse tloaelehileng kapa tse phahamisitsoeng, li-edematous papules li ajoa ka mokhoa o hlakileng
Sebopeho se bobebe hangata se hlahisa ho hlohlona ha bobebe (empa ho hlohlona ho ka ba matla haholo), matheba a bokhubelu ba pinki, a hlophisoa ka mokhoa o lekanang 'me a qala ka maphele. Qeto ea lekhopho ka hare ho matsatsi a 7-10 ke ntho e tloaelehileng ka mofuta ona oa lefu lena.
- Erythema multiforme major: liphofu tse tloaelehileng kapa tse phahamisitsoeng, li-edematous papules tse ajoang ka mokhoa o ts'oarellang ka ho ama lera le le leng kapa ho feta. Epidermal detachment e kenyelletsa karolo e ka tlase ho 10% ea sebaka sohle sa 'mele.
○ Kalafo - Lithethefatsi tsa OTC
Haeba e tsamaea le feberu (mocheso oa 'mele o ntseng o phahama), ho kgothaletswa ho etela sepetlele kapele kamoo ho ka khonehang.
Lithethefatsi tse belaelloang li lokela ho khaotsa. (mohlala, lithibela-mafu, li-nonsteroidal anti-inflammatory drugs)
Li-antihistamine tsa molomo tse kang cetirizine le loratadine bakeng sa ho hlohlona.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]